In vitro activities of OPC-17116, a new quinolone; ofloxacin; and sparfloxacin against Chlamydia pneumoniae-Reference-Cited by-同舟云学术

In vitro activities of OPC-17116, a new quinolone; ofloxacin; and sparfloxacin against Chlamydia pneumoniae

Published:1994-06 Issue:6 Volume:38 Page:1402-1403
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Roblin P M¹,Montalban G¹,Hammerschlag M R¹

Affiliation:

1. Department of Pediatrics, State University of New York Health Science Center at Brooklyn 11203.

Abstract

The in vitro susceptibilities of 12 strains of Chlamydia pneumonia to a new quinolone, OPC-17116; ofloxacin; and sparfloxacin were determined. OPC-17116 was slightly less active than sparfloxacin but more active than ofloxacin, with a MIC for 90% of strains tested and a minimal chlamydiacidal concentration for 90% of strains tested of 0.5 micrograms/ml.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.38.6.1402

Reference11 articles.

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4. In vitro activities of five quinolones against Chlamydia pneumoniae;Hammerschlag M. R.;Antimicrob. Agents Chemother.,1992

5. In vitro and in vivo antibacterial activities of a new quinolone, OPC-17116;Imada T.;Antimicrob. Agents Chemother.,1992

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