Effect of Novel A 2A Adenosine Receptor Agonist ATL 313 on Clostridium difficile Toxin A-Induced Murine Ileal Enteritis
Author:
Affiliation:
1. Faculty of Medicine, Federal University of Ceará, Ceará, Brazil
2. University of Virginia
3. Adenosine Therapeutics, LLC, Charlottesville, Virginia
4. Faculty of Medicine of Ribeirão Preto, São Paulo University, São Paulo, Brazil
Abstract
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
Link
https://journals.asm.org/doi/pdf/10.1128/IAI.74.5.2606-2612.2006
Reference45 articles.
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3. Bouma, M. G., F. A. van den Wildenberg, and W. A. Buurman. 1996. Adenosine inhibits cytokine release and expression of adhesion molecules by activated human endothelial cells. Am. J. Physiol.270:C522-C529.
4. Brito, G. A., B. A. Carneiro-Filho, R. B. Oriá, R. V. Destura, A. A. Lima, and R. L. Guerrant. 2005. Clostridium difficile toxin A induces intestinal epithelial cell apoptosis and damage: role of Gln and Ala-Gln in toxin A effects. Dig. Dis. Sci.50:1271-1278.
5. Brito, G. A., J. Fujji, B. A. Carneiro-Filho, A. A. Lima, T. Obrig, and R. L. Guerrant. 2002. Mechanism of Clostridium difficile toxin A-induced apoptosis in T84 cells. J. Infect. Dis.186:1438-1447.
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