Role of the Porphyromonas gingivalis InlJ Protein in Homotypic and Heterotypic Biofilm Development

Author:

Capestany Cindy A.1,Kuboniwa Masae1,Jung Il-Young1,Park Yoonsuk1,Tribble Gena D.1,Lamont Richard J.1

Affiliation:

1. Department of Oral Biology, College of Dentistry, University of Florida, Gainesville, Florida 32607

Abstract

ABSTRACT The oral pathogen Porphyromonas gingivalis expresses a homolog of the internalin family protein InlJ. Inactivation of inlJ reduced monospecies biofilm formation by P. gingivalis . In contrast, heterotypic P. gingivalis - Streptococcus gordonii biofilm formation was enhanced in the InlJ-deficient mutant. The results indicate a nuanced role for InlJ in regulating biofilm accumulations of P. gingivalis .

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

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