Plasmodium falciparum Kelch Propeller Polymorphisms in Clinical Isolates from Ghana from 2007 to 2016-Reference-Cited by-同舟云学术

Plasmodium falciparum Kelch Propeller Polymorphisms in Clinical Isolates from Ghana from 2007 to 2016

Published:2019-11 Issue:11 Volume:63 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Matrevi Sena A.¹,Opoku-Agyeman Philip¹,Quashie Neils B.¹²,Bruku Selassie¹,Abuaku Benjamin¹,Koram Kwadwo A.¹,Fox Anne³,Letizia Andrew³,Duah-Quashie Nancy O.¹^ORCID

Affiliation:

1. Department of Epidemiology, Noguchi Memorial Institute for Medical Research, College of Health Sciences, University of Ghana, Legon, Ghana

2. Centre for Tropical Clinical Pharmacology and Therapeutics, School of Medicine and Dentistry, College of Health Sciences, University of Ghana, Legon, Ghana

3. United States Naval Medical Research Unit 3, Ghana Laboratory, Accra, Ghana

Abstract

The continuous surveillance of polymorphisms in the kelch propeller domain of Plasmodium falciparum from Africa is important for the discovery of the actual markers of artemisinin resistance in the region. The information on the markers is crucial for control strategies involving chemotherapy and chemoprophylaxis for residents and nonimmune travelers to the country.

Funder

Global Fund to Fight AIDS, Tuberculosis and Malaria

DOD | MHS | Armed Forces Health Surveillance Branch

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00802-19

Reference39 articles.

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2. WHO. 2017. Artemisinin and artemisinin-based combination therapy resistance 2017. http://apps.who.int/iris/bitstream/10665/255213/1/WHO-HTM-GMP-2017.9-eng.pdf. Accessed 16 February 2018.

3. A molecular marker of artemisinin-resistant Plasmodium falciparum malaria

4. A Major Genome Region Underlying Artemisinin Resistance in Malaria

5. High Heritability of Malaria Parasite Clearance Rate Indicates a Genetic Basis for Artemisinin Resistance in Western Cambodia

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