Multivalent Interactions Drive the <i>Toxoplasma</i> AC9:AC10:ERK7 Complex To Concentrate ERK7 in the Apical Cap-Reference-Cited by-同舟云学术

Multivalent Interactions Drive the Toxoplasma AC9:AC10:ERK7 Complex To Concentrate ERK7 in the Apical Cap

Published:2022-02-22 Issue:1 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Back Peter S.¹^ORCID,O’Shaughnessy William J.²^ORCID,Moon Andy S.³,Dewangan Pravin S.²,Reese Michael L.²⁴^ORCID,Bradley Peter J.¹³^ORCID

Affiliation:

1. Molecular Biology Institute, University of California, Los Angeles, California, USA

2. Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, Texas, USA

3. Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, California, USA

4. Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas, USA

Abstract

The phylum Apicomplexa consists of obligate, intracellular parasites, including the causative agents of toxoplasmosis, malaria, and cryptosporidiosis. Hallmarks of these parasites are the IMC and the apical complex, both of which are unique structures that are conserved throughout the phylum and required for parasite survival.

Funder

HHS | National Institutes of Health

National Science Foundation

UC | University of California, Los Angeles

Welch Foundation

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.02864-21

Reference58 articles.