The Staphylococcus aureus CidA and LrgA Proteins Are Functional Holins Involved in the Transport of By-Products of Carbohydrate Metabolism-Reference-Cited by-同舟云学术

The Staphylococcus aureus CidA and LrgA Proteins Are Functional Holins Involved in the Transport of By-Products of Carbohydrate Metabolism

Published:2022-02-22 Issue:1 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Endres Jennifer L.¹,Chaudhari Sujata S.¹,Zhang Xinyan¹,Prahlad Janani¹,Wang Shu-Qi¹,Foley Lily A.¹,Luca Sorin¹,Bose Jeffrey L.²^ORCID,Thomas Vinai C.¹^ORCID,Bayles Kenneth W.¹

Affiliation:

1. Center for Staphylococcal Research, Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA

2. Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA

Abstract

The Staphylococcus aureus cidABC and lrgAB operons represent the founding members of a large, highly conserved family of genes that span multiple kingdoms of life. Despite the fact that they have been shown to be involved in bacterial PCD during biofilm development, very little is known about the molecular/biochemical functions of the proteins they encode.

Funder

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.02827-21

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