Pyelonephritis Therapy in Rats: Random Association with Excreted Urinary Antibacterial Activity-Reference-Cited by-同舟云学术

Pyelonephritis Therapy in Rats: Random Association with Excreted Urinary Antibacterial Activity

Published:1970-10 Issue:4 Volume:20 Page:598-599
ISSN:0003-6919
Container-title:Applied Microbiology
language:en
Short-container-title:Appl Microbiol

Author:

Burrous S. E.¹,Freedman R.¹,Chamberlain R. E.¹,Basson R. P.¹

Affiliation:

1. Eaton Laboratories, The Norwich Pharmacal Company, Norwich, New York 13815

Abstract

In vitro activities or excreted urinary activities of 56 generic and experimental drugs against two organisms commonly associated with human pyelonephritis, Escherichia coli and Proteus mirabilis , are not correlated with the in vivo activities of these compounds as measured by reduction of viable organisms in kidneys in experimental pyelonephritis.

Publisher

American Society for Microbiology

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

https://journals.asm.org/doi/pdf/10.1128/am.20.4.598-599.1970

Reference4 articles.

1. Rat pyelonephritis model suitable for primary or secondary screening;Burrous S. E.;Appl. Microbiol.,1969

2. Paul H. E. and M. F. Paul. 1964. The nitrofurans-chemotherapuetuc properties p. 307-369. In R. J. Schnitzer and F. Hawking (ed.) Experimental chemotherapy vol 2. Academic Press Inc. New York.

3. Antimicrobial susceptibility of pathogenic organisms isolated from the urinary tract in 1963;Schneierson S. S.;N. Y. State J. Med.,1965

4. The treatment of urinary tract infections with a new antibiotic-cephaloglycin;Trafton H. M.;J. Urol.,1969

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1. Effect of Antibacterial Therapy on Renal Lysozyme Levels in Rats Developing Bacterial Pyelonephritis;Antimicrobial Agents and Chemotherapy;1972-02