Ultrastructural localization and protective activity of a high-molecular-weight antigen isolated from Legionella pneumophila

Author:

Elliott J A,Johnson W,Helms C M

Abstract

Immunoperoxidase labeling showed that the F-1 antigen of Legionella pneumophila is located on the bacterial cell surface. Protection against lethal intraperitoneal challenge with serogroup 1 L. pneumophila was induced in guinea pigs by heat-killed cells and F-1 antigen from serogroup 1, but not by heat-killed cells or F-1 antigens from serogroup 2, 3, or 4.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference13 articles.

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4. The cell envelope of Legionnaires' disease bacterium: morphologic and biochemical characteristics;Flesher A. R.;Ann. Intern. Med.,1979

5. Identification of a cytotoxin produced by Legionella pneumophila;Friedman R. L.;Infect. Immun.,1980

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