Vaccination of Icelandic Children with the 10-Valent Pneumococcal Vaccine Leads to a Significant Herd Effect among Adults in Iceland

Author:

Quirk Sigríður J.123,Haraldsson Gunnsteinn123,Hjálmarsdóttir Martha Á.123,van Tonder Andries J.4,Hrafnkelsson Birgir5,Bentley Stephen D.4,Haraldsson Ásgeir16,Erlendsdóttir Helga123,Brueggemann Angela B.78,Kristinsson Karl G.123

Affiliation:

1. University of Iceland, Faculty of Medicine, Reykjavík, Iceland

2. Landspitali, University Hospital, Reykjavík, Iceland

3. BioMedical Centre of the University of Iceland, Reykjavík, Iceland

4. Parasites and Microbes, Wellcome Sanger Institute, Hinxton, United Kingdom

5. University of Iceland, Department of Mathematics, Reykjavík, Iceland

6. Children’s Hospital Iceland, Reykjavík, Iceland

7. Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom

8. Department of Medicine, Imperial College London, London, United Kingdom

Abstract

The introduction of pneumococcal conjugate vaccines (PCVs) into childhood vaccination programs has reduced carriage of vaccine serotypes and pneumococcal disease. The 10-valent PCV was introduced in Iceland in 2011.

Funder

The Wellcome Trust Research Fellowship

Wellcome core funding grant

Landspitali University Hospital Research Fund

The Eimskip University Fund

GlaxoSmithKline

Oxford University | John Fell Fund, University of Oxford

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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