Tn125-Related Acquisition ofblaNDM-Like Genes in Acinetobacter baumannii-Reference-Cited by-同舟云学术

Tn125-Related Acquisition ofblaNDM-Like Genes in Acinetobacter baumannii

Published:2011-12-05 Issue:2 Volume:56 Page:1087-1089
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob. Agents Chemother.

Author:

Poirel Laurent,Bonnin Rémy A.,Boulanger Anne,Schrenzel Jacques,Kaase Martin,Nordmann Patrice

Abstract

ABSTRACTA multidrug-resistantAcinetobacter baumanniiisolate recovered from a patient hospitalized in Switzerland after a transfer from Serbia produced the NDM-1 carbapenemase. TheblaNDM-1gene was part of a chromosomally located Tn125composite transposon bracketed by two copies of the same insertion sequence, ISAba125. This transposon was also associated with the acquisition and expression of theblaNDM-2gene in anA. baumanniiisolate in Germany. Tn125appears to be the main vehicle for dissemination ofblaNDMgenes in that species.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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