A Pilot Study for the Evaluation of an Interferon Gamma Release Assay (IGRA) To Measure T-Cell Immune Responses after SARS-CoV-2 Infection or Vaccination in a Unique Cloistered Cohort-Reference-Cited by-同舟云学术

A Pilot Study for the Evaluation of an Interferon Gamma Release Assay (IGRA) To Measure T-Cell Immune Responses after SARS-CoV-2 Infection or Vaccination in a Unique Cloistered Cohort

Published:2022-03-16 Issue:3 Volume:60 Page:
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Barreiro Pablo¹^ORCID,Sanz Juan Carlos¹,San Román Jesús¹,Pérez-Abeledo Marta¹,Carretero Mar¹,Megías Gregoria²,Viñuela-Prieto José Manuel¹,Ramos Belén¹,Canora Jesús¹,Martínez-Peromingo Francisco Javier¹,Barba Raquel¹,Zapatero Antonio¹,Candel Francisco Javier¹

Affiliation:

1. Regional Laboratory of Public Health, Hospital Enfermera Isabel Zendal, Madrid, Spain

2. Unit of Microbiology, Hospital Universitario de Burgos, Burgos, Spain

Abstract

Assessment of T-cell responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigens may be of value to determine long-lasting protection to breakthrough infections or reinfections. Interferon gamma release assay is a validated method to test cellular immunity in mycobacterial infections and has been proposed for patients with SARS-CoV-2 infection or vaccination.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/jcm.02199-21

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