In VitroActivities of Eight Antifungal Drugs against 104 Environmental and Clinical Isolates of Aureobasidium pullulans

Abstract

ABSTRACTAureobasidium pullulansis an unusual agent of phaeohyphomycosis. Thein vitroactivities of antifungals against 104 isolates ofAureobasidium pullulansvar.pullulansandA. pullulansvar.melanigenumrevealed low MIC90s of amphotericin B, posaconazole, and itraconazole. However, they were resistant to fluconazole (≥64 μg/ml) and had high MICs of voriconazole, isavuconazole, caspofungin, and micafungin.