Commentary: Impact of CLSI Breakpoint Changes on Microbiology Laboratories and Antimicrobial Stewardship Programs-Reference-Cited by-同舟云学术

Commentary: Impact of CLSI Breakpoint Changes on Microbiology Laboratories and Antimicrobial Stewardship Programs

Published:2016-04 Issue:4 Volume:54 Page:840-844
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Heil Emily L.¹,Johnson J. Kristie²

Affiliation:

1. Department of Pharmacy, University of Maryland Medical Center, Baltimore, Maryland, USA

2. Department of Pathology, University of Maryland School of Medicine, Baltimore, Maryland, USA

Abstract

ABSTRACT In 2010, the Clinical and Laboratory Standards Institute (CLSI) lowered the MIC breakpoints for many beta-lactam antibiotics to enhance detection of known resistance among Enterobacteriaceae . The decision to implement these new breakpoints, including the changes announced in both 2010 and 2014, can have a significant impact on both microbiology laboratories and antimicrobial stewardship programs. In this commentary, we discuss the changes and how implementation of these updated CLSI breakpoints requires partnership between antimicrobial stewardship programs and the microbiology laboratory, including data on the impact that the changes had on antibiotic usage at our own institution.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.02424-15

Reference21 articles.

1. CLSI. 2010. Performance standards for antimicrobial susceptibility testing: 20th informational supplement, CLSI document M100-S20. Clinical and Laboratory Standards Institute, Wayne, PA.

2. CLSI. 2014. Performance standards for antimicrobial susceptibility testing: 24th informational supplement, CLSI document M100-S24. Clinical and Laboratory Standards Institute, Wayne, PA.

3. The European Committee on Antimicrobial Susceptibility Testing. 2015. Breakpoint tables for interpretation of MICs and zone diameters. Version 5.0 2015. http://www.eucast.org.

4. Extended-Spectrum β-Lactamase Producers Reported as Susceptible to Piperacillin-Tazobactam, Cefepime, and Cefuroxime in the Era of Lowered Breakpoints and No Confirmatory Tests

5. Incidence of Extended-Spectrum- -Lactamase-Producing Escherichia coli and Klebsiella pneumoniae Isolates That Test Susceptible to Cephalosporins and Aztreonam by the Revised CLSI Breakpoints

Cited by 37 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Metallo-β-lactamase SMB-1 evolves into a more efficient hydrolase under the selective pressure of meropenem;Journal of Inorganic Biochemistry;2023-10

2. Reporting antimicrobial susceptibilities and phenotypes of resistance to vancomycin in vancomycin-resistant Enterococcus spp. clinical isolates: A nationwide proficiency study;Enfermedades infecciosas y microbiologia clinica (English ed.);2023-06

3. Phenotypes, genotypes and breakpoints: an assessment of β-lactam/β-lactamase inhibitor combinations against OXA-48;Journal of Antimicrobial Chemotherapy;2023-01-10

4. Clinical Outcomes of Children With Extended-spectrum ß -Lactamase Urinary Tract Infection Receiving Discordant Empiric Antibiotic: A Comparative Study of Fever Duration, Length of Stay, and Readmissions;Clinical Pediatrics;2022-10-05

5. Chemical Composition and Antimicrobial Properties of Teucrium polium Essential Oil Collected from Dena Mountain in Yasuj, Iran;Journal of Clinical Care and Skills;2022-09-01