Identification of 14-α-Lanosterol Demethylase (CYP51) in Scedosporium Species

Author:

Bernhardt Anne1,Meyer Wieland23,Rickerts Volker1,Aebischer Toni1,Tintelnot Kathrin1

Affiliation:

1. Mycotic and Parasitic Agents and Mycobacteria, Department of Infectious Diseases, Robert Koch Institute, Berlin, Germany

2. Molecular Mycology Research Laboratory, Centre for Infectious Diseases and Microbiology, Sydney Medical School, The University of Sydney, Westmead Hospital, Westmead Institute for Medical Research, Westmead, Australia

3. Marie Bashir Institute for Infectious Diseases and Biosecurity, The University of Sydney, Sydney, Australia

Abstract

Scedosporium spp. cause infections (scedosporiosis) in both immunocompetent and immunocompromised individuals and may persistently colonize the respiratory tract in patients with cystic fibrosis (CF).

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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