In Vitro Activity of Netilmicin

Author:

Smith J. A.1,Morgan J. R.2,Mogyoros M.2

Affiliation:

1. Division of Microbiology, Mount Sinai Hospital,* Toronto, Ontario, Canada

2. Departments of Medical Microbiology and Medicine, University of Toronto, Toronto, Ontario, Canada

Abstract

The activity of netilmicin against a variety of bacteria was similar to that of gentamicin, sisomicin, and tobramycin, but it was less active than these three drugs against Pseudomonas aeruginosa . Synergy with penicillin G against enterococci was demonstrated.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference7 articles.

1. Comparison of sisomicin and gentamicin in bacteriuric patients with underlying disease of the urinary tract;Klastersky S.;Antimicrob. Agents Chemother.,1975

2. In vitro comparison of four aminoglycoside antibiotics: sisomicin, gentamicin, tobramycin, and BB-K8;Levison M. E.;Antimicrob. Agents Chemother.,1974

3. Comparison of the antibacterial activities of sisomicin and gentamicin against gram-negative bacteria;Meyers B. R.;Antimicrob. Agents Chemother.,1975

4. Studies on antibiotic synergism against enterococci;Moellering R. C.;J. Lab. Clin. Med.,1971

5. Penicillin-tobramycin synergism against enterococci: a comparison with penicillin and gentamicin;Moellering R. C.;Antimicrob. Agents Chemother.,1975

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1. Sisomicin and Netilmicin;Kucers' The Use of Antibiotics Sixth Edition;2010-10-29

2. THE IN VITRO ACTIVITY OF GENTAMICIN, TOBRAMYCIN AND NETILMICIN AGAINST 500 CLINICAL ISOLATES OF BACTERIA;Acta Pathologica Microbiologica Scandinavica Series B: Microbiology;2009-08-15

3. Comparative bactericidal activity of penicillin-netilmicin and penicillin-gentamicin against enterococci;Journal of Antimicrobial Chemotherapy;1986

4. New Drug Evaluations: Netilmicin (Netromycin, Schering-Plough);Drug Intelligence & Clinical Pharmacy;1983-02

5. Assay of netilmicin, using enzyme immunoassay for gentamicin;Antimicrobial Agents and Chemotherapy;1982-03

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