Properties of Allyl Alcohol-Resistant Mutants of Clostridium butyricum Grown on Glycerol

Author:

Abbad-Andaloussi S,Amine J,Gerard P,Petitdemange E,Petitdemange H

Abstract

Mutants of Clostridium butyricum E5 exhibiting resistance to allyl alcohol which produced the same quantities of 1,3-propanediol as the wild-type strain but more acetate than butyrate were isolated. The acetate-butyrate formation plays a major function in the regulation of the internal redox balance. Allyl alcohol resistance can be attributed not to the loss of 1,3-propanediol dehydrogenase but to a shift in the reductive properties of the enzyme. The data support the view that cellular regulation is modified to avoid intracellular accumulation of 3-hydroxypropionaldehyde.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Reference11 articles.

1. Glycerol dehydratase activity: the limiting step for the 1,3-propanediol production by Clostridium butyricum DSM 5431;Abbad-Andaloussi S.;Lett. Appl. Microbiol.,1996

2. Isolation and characterization of Clostridium butyricum DSM 5431 mutants with increased resistance to 1,3-propanediol and altered production of acids;Abbad-Andaloussi S.;Appl. Environ. Microbiol.,1995

3. Production of a broad spectrum antimicrobial substance by Lactobacillus reuteri;Axelsson L.;Microb. Ecol. Health Dis.,1989

4. Biebl H. Personal communication.

5. Purification of 1,3-propanediol dehydrogenase from Citrobacter freundii and cloning, sequencing, and overexpressing of the corresponding gene in Escherichia coli;Daniel R.;J. Bacteriol.,1995

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3