Role of VP30 Phosphorylation in Ebola Virus Nucleocapsid Assembly and Transport

Author:

Takamatsu Yuki1234,Yoshikawa Tomoki2,Kurosu Takeshi2,Fukushi Shuetsu2,Nagata Noriyo5ORCID,Shimojima Masayuki2,Ebihara Hideki2,Saijo Masayuki2ORCID,Noda Takeshi1ORCID

Affiliation:

1. Laboratory of Ultrastructural Virology, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan

2. Department of Virology I, National Institute of Infectious Diseases, Tokyo, Japan

3. Institut für Virologie, Philipps-Universität Marburg, Marburg, Germany

4. Department of Virology, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan

5. Department of Pathology, National Institute of Infectious Diseases, Tokyo, Japan

Abstract

Ebola virus (EBOV) causes severe fevers with unusually high case fatality rates. The nucleocapsid provides the template for viral genome transcription and replication.

Funder

MEXT | Japan Society for the Promotion of Science

Japan Agency for Medical Research and Development

The Ichiro Kurane Foundation for the Promotion of Medical Science & Medical Care

MSD Life Science Foundation, Public Interest Incorporated Foundation

Japan Research Foundation for Clinical Pharmacology

Terumo Life Science Foundation

Waksman Foundation of Japan

Naito Foundation

Takeda Science Foundation

Novartis Foundation

Cooperative Research Grant(s) from the Joint Usage/Research Center on Tropical Disease, Institute of Tropical Medicine, Nagasaki University

Institute for Frontier Life and Medical Sciences, Kyoto University

JSPS Core-to-Core Program A, the Advanced Research Networks; the JST Core Research for Evolutional Science and Technology

Grant for Joint Research Project of the Institute of Medical Science, University of Tokyo

Joint Usage/Research Center program of Institute for Frontier Life and Medical Sciences Kyoto University

the Joint Usage/Research Center on Tropical Disease, Nagasaki University

Uehara Memorial Foundation

Daiichi Sankyo Foundation of Life Science

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

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