Genetic Analysis of the Role of the Conserved Inner Membrane Protein CvpA in Enterohemorrhagic Escherichia coli Resistance to Deoxycholate-Reference-Cited by-同舟云学术

Genetic Analysis of the Role of the Conserved Inner Membrane Protein CvpA in Enterohemorrhagic Escherichia coli Resistance to Deoxycholate

Published:2021-02-22 Issue:6 Volume:203 Page:
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Warr Alyson R.¹²^ORCID,Giorgio Rachel T.¹,Waldor Matthew K.¹²³^ORCID

Affiliation:

1. Department of Microbiology, Harvard Medical School, Boston, Massachusetts, USA

2. Division of Infectious Disease, Brigham and Women’s Hospital, Boston, Massachusetts, USA

3. Howard Hughes Medical Institute, Boston, Massachusetts, USA

Abstract

Several enteric pathogens, including enterohemorrhagic E. coli (EHEC) strains, require CvpA to robustly colonize the intestine. This inner membrane protein is also important for secretion of a colicin and for EHEC resistance to the bile salt deoxycholate (DOC), but its function is unknown.

Funder

HHS | National Institutes of Health

Howard Hughes Medical Institute

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.00661-20

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