Correlation of Clinical Outcomes with β-Glucan Levels in Patients with Invasive Candidiasis-Reference-Cited by-同舟云学术

Correlation of Clinical Outcomes with β-Glucan Levels in Patients with Invasive Candidiasis

Published:2012-06 Issue:6 Volume:50 Page:2104-2106
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Sims Charles R.¹,Jaijakul Siraya¹,Mohr John²,Rodriguez Jose¹,Finkelman Malcolm³,Ostrosky-Zeichner Luis¹

Affiliation:

1. Laboratory of Mycology Research, Division of Infectious Diseases, University of Texas Health Science Center at Houston, Houston, Texas, USA

2. Cubist Pharmaceuticals, Lexington, Massachusetts, USA

3. Associates of Cape Cod, Falmouth, Massachusetts, USA

Abstract

ABSTRACT The correlation of β-glucan (BG) levels with clinical outcomes in invasive candidiasis (IC) remains unknown. Patients with proven IC were followed prospectively from diagnosis to outcome with twice-weekly serum BG sampling. Correlation of BG with clinical outcome was assessed in each patient. BG levels tend to decrease in successfully treated patients and increase in treatment failures. BG levels may be useful as surrogates for outcome evaluation of IC.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.00773-12

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