Gentamicin- and Cephalothin-Associated Rises in Blood Urea Nitrogen-Reference-Cited by-同舟云学术

Gentamicin- and Cephalothin-Associated Rises in Blood Urea Nitrogen

Published:1976-07 Issue:1 Volume:10 Page:80-82
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Fanning W. Lee¹²,Gump Dieter¹²,Jick Hershel¹²

Affiliation:

1. Infectious Disease Unit, Medical College of Vermont, Burlington, Vermont 05401

2. Boston University School of Medicine, Waltham, Massachusetts 02154

Abstract

Standardized rates of drug-attributed rises in blood urea nitrogen were 8.6%, 2.9%, and 9.3%, respectively, in patients receiving gentamicin alone, cephalothin alone, and both drugs together. These results provide evidence against a substantial synergism between the two drugs in the production of impaired renal function.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.10.1.80

Reference14 articles.

1. Anuria and acute tubular necrosis associated with gentamicin and cephalothin;Bobrow S. N.;J. Am. Med. Assoc.,1972

2. Acute renal failure during cephalothin therapy;Burton J.;J. Am. Med. Assoc.,1974

3. Nephrotoxicity of combined cephalothingentamicin regimen;Cabanillas F.;Arch. Intern. Med.,1975

4. Adverse reactions to antimicrobial agents;Caldwell J.;J. Am. Med. Assoc.,1974

5. Nephrotoxicity associated with cephalothin administration;Carling P.;Arch. Intern. Med.,1975

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