Pathogenic Escherichia coli-Specific Bacteriophages and Polyvalent Bacteriophages in Piglet Guts with Increasing Coliphage Numbers after Weaning

Author:

Lin Yan123,Zhou Bei12,Zhu Weiyun123ORCID

Affiliation:

1. Laboratory of Gastrointestinal Microbiology, Jiangsu Key Laboratory of Gastrointestinal Nutrition and Animal Health, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China

2. National Center for International Research on Animal Gut Nutrition, Nanjing Agricultural University, Nanjing, China

3. Joint International Research Laboratory of Animal Health and Food Safety, Nanjing Agricultural University, Nanjing, China

Abstract

Previous studies based on metagenomic sequencing reported that gut bacteriophages profoundly influence gut physiology but did not provide information regarding the host range and biological significance. Here, we screened coliphages from preweaned and postweaned piglet gut against indicator hosts, which allowed us to identify the pathogenic E. coli -specific bacteriophages and polyvalent bacteriophages in pig farms and quantify their presence.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangsu Province

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

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