Clostridium difficile Ribotype Diversity at Six Health Care Institutions in the United States

Author:

Waslawski Sheila1,Lo Eugene S.1,Ewing Sarah A.1,Young Vincent B.12,Aronoff David M.12,Sharp Susan E.3,Novak-Weekley Susan M.4,Crist Arthur E.5,Dunne W. Michael67,Hoppe-Bauer Joan7,Johnson Michelle7,Brecher Stephen M.8,Newton Duane W.9,Walk Seth T.110

Affiliation:

1. Department of Internal Medicine, Division of Infectious Diseases, University of Michigan Hospital and Health Systems, Ann Arbor, Michigan, USA

2. Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA

3. Kaiser Permanente-NW, Portland, Oregon, USA

4. Southern California Permanente Medical Group Regional Reference Laboratories, North Hollywood, California, USA

5. Department of Laboratory Services, Division of Clinical Microbiology, York Hospital, York, Pennsylvania, USA

6. bioMérieux, Durham, North Carolina

7. Department of Microbiology, Barnes-Jewish Hospital, St. Louis, Missouri, USA

8. VA Boston Healthcare System, Boston, Massachusetts, USA

9. Clinical Microbiology Laboratories, Department of Pathology, University of Michigan Hospital and Health Systems, Ann Arbor, Michigan, USA

10. Department of Microbiology, Montana State University, Bozeman, Montana, USA

Abstract

ABSTRACT Capillary-based PCR ribotyping was used to quantify the presence/absence and relative abundance of 98 Clostridium difficile ribotypes from clinical cases of disease at health care institutions in six states of the United States. Regionally important ribotypes were identified, and institutions in close proximity did not necessarily share more ribotype diversity than institutions that were farther apart.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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