Chagas Disease in the United States: a Public Health Approach

Author:

Bern Caryn1,Messenger Louisa A.2,Whitman Jeffrey D.1,Maguire James H.3

Affiliation:

1. University of California San Francisco School of Medicine, San Francisco, California, USA

2. London School of Hygiene and Tropical Medicine, London, UK

3. Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

Abstract

Trypanosoma cruzi is the etiological agent of Chagas disease, usually transmitted by triatomine vectors. An estimated 20 to 30% of infected individuals develop potentially lethal cardiac or gastrointestinal disease. Sylvatic transmission cycles exist in the southern United States, involving 11 triatomine vector species and infected mammals such as rodents, opossums, and dogs. Nevertheless, imported chronic T. cruzi infections in migrants from Latin America vastly outnumber locally acquired human cases.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Microbiology (medical),Public Health, Environmental and Occupational Health,General Immunology and Microbiology,Epidemiology

Reference352 articles.

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4. World Health Organization. 2018. Global health estimates 2016 summary tables: DALYs by cause age and sex by WHO region 2000–2016. World Health Organization Geneva Switzerland. https://www.who.int/healthinfo/global_burden_disease/GHE2016_DALY_WHOReg_2000_2016_.xls?ua=1.

5. López-Vélez R, Norman FF, Bern C. 2019. American trypanosomiasis (Chagas disease), p 762–765. In Ryan ET, Hill DR, Solomon T, Endy TP, Aronson N (ed), Hunter’s tropical medicine and emerging infectious disease, 10th ed. Elsevier, London, United Kingdom.

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