Affiliation:
1. Department of Clinical Microbiology, Hospital Clínico San Carlos, 28040 Madrid, Spain
Abstract
ABSTRACT
The rates of resistance to erythromycin and clindamycin among
Streptococcus agalactiae
strains isolated in our hospital increased from 4.2 and 0.8% in 1993 to 17.4 and 12.1%, respectively, in 2001. Erythromycin resistance was mainly due to the presence of an Erm(B) methylase, while the M phenotype was detected in 3.8% of the strains. Telithromycin was very active against erythromycin-resistant strains, irrespective of their mechanisms of macrolide resistance.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Reference21 articles.
1. Andrews, J. I., D. J. Diekema, S. K. Hunter, P. R. Rhomberg, M. A. Pfaller, R. N. Jones, and G. V. Doern. 2000. Group B streptococci causing neonatal bloodstream infection: antimicrobial susceptibility and serotyping results from SENTRY centers in the Western Hemisphere. Am. J. Obstet. Gynecol.183:859-862.
2. Barry, A. L., P. C. Fuchs, and S. D. Brown. 2001. Relative potency of telithromycin, azithromycin and erythromycin against recent clinical isolates of gram-positive cocci. Eur. J. Clin. Microbiol. Infect. Dis.20:494-497.
3. Antibiotic resistance and penicillin tolerance in clinical isolates of group B streptococci
4. Centers for Disease Control and Prevention. 1996. Prevention of perinatal group B streptococcal disease: a public health perspective. Morb. Mortal. Wkly. Rep.45:1-24.
5. Macrolide and Tetracycline Resistance and Molecular Relationships of Clinical Strains of
Streptococcus agalactiae
Cited by
68 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献