Medium-Chain-Length Fatty Acid Catabolism in Cupriavidus necator H16: Transcriptome Sequencing Reveals Differences from Long-Chain-Length Fatty Acid β-Oxidation and Involvement of Several Homologous Genes-Reference-Cited by-同舟云学术

Medium-Chain-Length Fatty Acid Catabolism in Cupriavidus necator H16: Transcriptome Sequencing Reveals Differences from Long-Chain-Length Fatty Acid β-Oxidation and Involvement of Several Homologous Genes

Published:2023-01-31 Issue:1 Volume:89 Page:
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Strittmatter Carl Simon¹^ORCID,Poehlein Anja²^ORCID,Himmelbach Axel³,Daniel Rolf²^ORCID,Steinbüchel Alexander¹⁴^ORCID

Affiliation:

1. Institut für Molekulare Mikrobiologie und Biotechnologie, Westfälische Wilhelms-University Münster, Münster, Germany

2. Genomic and Applied Microbiology & Göttingen Genomic Laboratory, Institute of Microbiology and Genetics, Georg-August University of Göttingen, Göttingen, Germany

3. Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Seeland, Germany

4. Environmental Science Department, King Abdulaziz University, Jeddah, Saudi Arabia

Abstract

Although Cupriavidus necator H16 has been used in several studies to produce polyhydroxyalkanoates from various lipids, the fatty acid metabolism is poorly understood. The β-oxidation of long-chain-length FAs has been investigated, but the tremendous number of homologous genes encoding β-oxidation enzymes hides the potential for variances in the expressed genes for catabolism of shorter FAs.

Funder

Rahn-Quade Stiftung

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/aem.01428-22

Reference78 articles.

1. The Classical, Yet Controversial, First Enzyme of Lipid Synthesis: Escherichia coli Acetyl-CoA Carboxylase

2. Fatty acid biosynthesis revisited: structure elucidation and metabolic engineering

3. A new Escherichia coli metabolic competency: growth on fatty acids by a novel anaerobic β-oxidation pathway

4. Regulation of fatty acid degradation in Escherichia coli: analysis by operon fusion

5. Regulation of fatty acid metabolism in bacteria

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