Monitoring of Stool Microbiota in Subjects with Diarrhea Indicates Distortions in Composition

Author:

Mai Volker1,Braden Christopher R.2,Heckendorf Jill1,Pironis Baiba1,Hirshon Jon Mark13

Affiliation:

1. Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, Maryland

2. Enteric Diseases Epidemiology Branch, Division of Foodborne, Bacterial, and Mycotic Diseases, National Center for Zoonotic, Vectorborne, and Enteric Diseases, Centers for Disease Control and Prevention, Atlanta Georgia

3. Department of Emergency Medicine, University of Maryland School of Medicine, Baltimore, Maryland

Abstract

ABSTRACT We utilized denaturing gradient gel electrophoresis profiling to survey stool microbiota in 175 persons with diarrhea and 113 asymptomatic persons in a diarrhea surveillance study. Compared with healthy controls, the microbiota profiles in diarrhea cases more frequently exhibited decreased diversity and strong bands indicating the overgrowth of selected bacteria or bacterial groups.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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1. Gut microbiome of a porcine model of metabolic syndrome and HF-pEF;American Journal of Physiology-Heart and Circulatory Physiology;2020-03-01

2. Bacteriophages Reduce Pathogenic Escherichia coli Counts in Mice Without Distorting Gut Microbiota;Frontiers in Microbiology;2019-09-10

3. Mass Azithromycin Distribution and Community Microbiome: A Cluster-Randomized Trial;Open Forum Infectious Diseases;2018-07-24

4. Postinfection Irritable Bowel Syndrome;Journal of Clinical Gastroenterology;2017-11

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