Epidemiology and Molecular Basis of Multidrug Resistance in Rhodococcus equi

Author:

Álvarez-Narváez Sonsiray1ORCID,Huber Laura2ORCID,Giguère Steeve3,Hart Kelsey A.3,Berghaus Roy D.4,Sanchez Susan1,Cohen Noah D.5ORCID

Affiliation:

1. Athens Veterinary Diagnostic Laboratory, Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA

2. Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, Alabama, USA

3. Department of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA

4. Department of Population Health, Food Animal Health and Management, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA

5. Department of Large Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, USA

Abstract

The development and spread of antimicrobial resistance are major concerns for human and animal health. The effects of the overuse of antimicrobials in domestic animals on the dissemination of resistant microbes to humans and the environment are of concern worldwide. Rhodococcus equi is an ideal model to illustrate the spread of antimicrobial resistance at the animal-human-environment interface because it is a natural soil saprophyte that is an intracellular zoonotic pathogen that produces severe bronchopneumonia in many animal species and humans.

Funder

Hodgson Chair in Equine Research

Link Equine Research Endowment, Texas A&M University

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology,Infectious Diseases

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