The Race between Host Antiviral Innate Immunity and the Immune Evasion Strategies of Herpes Simplex Virus 1-Reference-Cited by-同舟云学术

The Race between Host Antiviral Innate Immunity and the Immune Evasion Strategies of Herpes Simplex Virus 1

Published:2020-11-18 Issue:4 Volume:84 Page:
ISSN:1092-2172
Container-title:Microbiology and Molecular Biology Reviews
language:en
Short-container-title:Microbiol Mol Biol Rev

Author:

Zhu Huifang¹²,Zheng Chunfu¹³^ORCID

Affiliation:

1. Department of Immunology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China

2. Neonatal/Pediatric Intensive Care Unit, Children's Medical Center, First Affiliated Hospital of Gannan Medical University, Ganzhou, China

3. Department of Microbiology, Immunology and Infectious Diseases, University of Calgary, Calgary, Alberta, Canada

Abstract

Herpes simplex virus 1 (HSV-1) is very successful in establishing acute and latent infections in humans by counteracting host antiviral innate immune responses. HSV-1 has evolved various strategies to evade host antiviral innate immunity and some cellular survival-associated pathways. Since there is still no vaccine available for HSV-1, a continuous update of information regarding the interaction between HSV-1 infection and the host antiviral innate immunity will provide novel insights to develop new therapeutic strategies for HSV-1 infection and its associated diseases.

Funder

Science and Technology Program of Fujian

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology,Infectious Diseases

Link

https://journals.asm.org/doi/pdf/10.1128/MMBR.00099-20

Reference243 articles.

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