Staphylococcal Biofilm Development: Structure, Regulation, and Treatment Strategies-Reference-Cited by-同舟云学术

Staphylococcal Biofilm Development: Structure, Regulation, and Treatment Strategies

Published:2020-08-19 Issue:3 Volume:84 Page:
ISSN:1092-2172
Container-title:Microbiology and Molecular Biology Reviews
language:en
Short-container-title:Microbiol Mol Biol Rev

Author:

Schilcher Katrin¹^ORCID,Horswill Alexander R.¹²^ORCID

Affiliation:

1. Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA

2. Department of Veterans Affairs Eastern Colorado Health Care System, Denver, Colorado, USA

Abstract

In many natural and clinical settings, bacteria are associated with some type of biotic or abiotic surface that enables them to form biofilms, a multicellular lifestyle with bacteria embedded in an extracellular matrix. Staphylococcus aureus and Staphylococcus epidermidis , the most frequent causes of biofilm-associated infections on indwelling medical devices, can switch between an existence as single free-floating cells and multicellular biofilms. During biofilm formation, cells first attach to a surface and then multiply to form microcolonies.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

U.S. Department of Veterans Affairs

American Heart Association

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology,Infectious Diseases

Link

https://journals.asm.org/doi/pdf/10.1128/MMBR.00026-19

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