Pluronic polyols in human lymphocyte cell line cultures

Author:

Mizrahi A

Abstract

Pluronic polyols markedly improved the growth of two human lymphocyte cell lines when added to the growth medium in concentrations of 0.05 to 0.1%. The results of the current studies suggest that, in addition to the protective effect of polyols against mechanical damage of mammalian cells in submerged cultures, the pluronic compounds may also, by lowering surface tension, facilitate transport of metabolites into cells and thus increase the growth rate.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference16 articles.

1. BASF Wyandotte Corporation. 1968. Determination of pluronic polyols Method no. F-3133. BASF Wyandotte Corp. Wyandotte Mich.

2. BASF Wyandotte Corporation. 1971. Catalogue F-3025. BASF Wyandotte Corp. Wyandotte Mich.

3. Production of Iymphotoxin and migration inhibition factor by established human lymphocyte cell lines;Granger G. A.;J. Immunol.,1970

4. The cultivation of animal cells at controlled dissolved oxygen partial pressure;Kilbum D. G.;Biotechnol. Bioeng.,1968

5. Secondary factors in fermentation processes;Margalith P.;Adv. Appl. Microbiol.,1964

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