Effect of anti-mu-chain-specific immunosuppression on Chikungunya virus encephalitis of mice-Reference-Cited by-同舟云学术

Effect of anti-mu-chain-specific immunosuppression on Chikungunya virus encephalitis of mice

Published:1977-06 Issue:3 Volume:16 Page:849-852
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Giovarelli M,Viano I,Zucca M,Valbonesi R,Dianzani F

Abstract

Mice neonatally immunosuppressed with anti-mu antiserum failed to produce circulating antibodies to sheep erythrocytes and showed a marked decrease in circulating immunoglobulins. However, when they were intracerebrally infected with Chikungunya virus (a group A togavirus), they showed a mortality rate consistently lower than non-immunosuppressed control mice. Several possible explanations for this finding are discussed.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.16.3.849-852.1977

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