Author:
Brumfitt W,Hamilton-Miller J M
Abstract
Forty-four patients (43 female, 1 male), all with a history of recurrent urinary tract infections, were treated with 250 mg of amoxicillin plus 125 mg of clavulanic acid (one tablet of Augmentin) every 8 h for 7 days. The microbiological cure rates were 84% 1 week after the end of treatment and 67% 1 month later. Side effects, which were reported by 20% of the patients, were mild and in no case caused interruption of treatment. In view of the increasing trend in resistance to agents commonly used for the treatment of urinary tract infections in outpatients, the combination of amoxicillin and clavulanic acid may now be considered a first-line drug in patients with recurrent urinary tract infections.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Reference19 articles.
1. Treatment of acute maxillary sinusitis V Amoxicillin, azidocillin, phenylpropanolamine and pivampicillin;Axelsson A.;Acta Otolaryngol.,1981
2. Brumfitt W. 1972. Bacterial aspects of renal disease p. 367-397. In D. A. K. Black (ed.) Renal disease 3rd ed. Blackwell Oxford.
3. Rifaprim (rifampin + trimethoprim): a comparative trial with cephradine in patients with recurrent urinary infection. Proc. 11th;Brumfitt W.;Int. Congr. Chemother.,1980
4. Brumfitt W. and J. M. T. Hamilton-Miller. 1983. Differential sensitivities to amoxycillin/clavulanate and amoxycillin in general practice urinary infections. Lancet ii:566.
5. The phenomenon of resistance to "Augmentin;Brumfitt W.;J. Clin. Pathol.,1983
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