Author:
Bille J,Edson R S,Roberts G D
Abstract
In a comparative fungal blood culture study, a lysis-centrifugation system (Isolator; Du Pont Co., Wilmington, Del.) detected 89% of all episodes of fungemia; the lysis-centrifugation system detected fungemia exclusively or significantly earlier than did a biphasic brain heart infusion bottle system 83% of the time. The lysis-centrifugation system was particularly useful in the early detection of fungemia caused by Candida tropicalis and Candida glabrata. In 53% of the clinically significant episodes, the earlier detection was directly helpful in the management of patients with fungemia. High-magnitude candidemia (greater than 5 CFU/ml of blood) was significantly associated with the presence of an infected intravascular catheter and with Candida species other than Candida albicans. The lysis-centrifugation system was sensitive in the detection of fungemia during the monitoring of patients receiving antifungal agents or after removal of an infected intravascular catheter.
Publisher
American Society for Microbiology
Reference9 articles.
1. Retrospective comparison of three blood culture media for the recovery of yeasts from clinical specimens;Bille J.;Eur. J. Clin. Microbiol.,1983
2. Evaluation of a Iysis-centrifugation system for the recovery of yeasts and filamentous fungi from blood;Bille J.;J. Clin. Microbiol.,1983
3. Neonatal Escherichia coli septicemia-bacterial counts in blood;Dietzman D. E.;J. Pediatr.,1974
4. Improved blood culture technique based on centrifugation: clinical evaluation;Dorn G. L.;J. Clin. Microbiol.,1979
5. New centrifugation blood culture device;Dorn G. L.;J. Clin. Microbiol.,1978
Cited by
80 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献