Aspergillus Galactomannan Antigen in the Cerebrospinal Fluid of Bone Marrow Transplant Recipients with Probable Cerebral Aspergillosis-Reference-Cited by-同舟云学术

Aspergillus Galactomannan Antigen in the Cerebrospinal Fluid of Bone Marrow Transplant Recipients with Probable Cerebral Aspergillosis

Published:2002-04 Issue:4 Volume:40 Page:1496-1499
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Viscoli Claudio¹²,Machetti Marco¹,Gazzola Paola¹³,De Maria Andrea⁴,Paola Dimitri⁵,Van Lint Maria Teresa⁶,Gualandi Francesca⁶,Truini Mauro⁷,Bacigalupo Andrea⁶

Affiliation:

1. Istituto Nazionale per la Ricerca sul Cancro

2. Dipartimento di Oncologia, Biologia e Genetica

3. Dipartimento di Scienze Neurologiche e della Visione

4. Dipartimento di Medicina Interna

5. Dipartimento di Medicina Sperimentale

6. Ospedale San Martino, Genoa, Italy

7. Dipartimento Diagnostico di Laboratorio, di Anatomia Patologica e Medico Legale, Università di Genova

Abstract

ABSTRACT The Aspergillus galactomannan test was performed on cerebrospinal fluid and serum samples from 5 patients with probable cerebral aspergillosis and from 16 control patients. Cerebrospinal fluid galactomannan levels were significantly higher in aspergillosis patients, and most galactomannan was produced intrathecally. Comparison of serum galactomannan values in pulmonary and cerebral aspergillosis patients showed significant overlapping. Detection of Aspergillus galactomannan in cerebrospinal fluid may be diagnostic of cerebral aspergillosis.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.40.4.1496-1499.2002

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