Foamy virus vectors-Reference-Cited by-同舟云学术

Foamy virus vectors

Published:1996-01 Issue:1 Volume:70 Page:217-222
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Russell D W¹,Miller A D¹

Affiliation:

1. Fred Hutchinson Cancer Research Center, Seattle, Washington 98104, USA.

Abstract

Human foamy virus (HFV) is a retrovirus of the spumavirus family. We have constructed vectors based on HFV that encode neomycin phosphotransferase and alkaline phosphatase. These vectors are able to transduce a wide variety of vertebrate cells by integration of the vector genome. Unlike vectors based on murine leukemia virus, HFV vectors are not inactivated by human serum, and they transduce stationary-phase cultures more efficiently than murine leukemia virus vectors. These properties, as well as their large packaging capacity, make HFV vectors promising gene transfer vehicles.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.70.1.217-222.1996

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