Structural and Evolutionary Analysis of an Orangutan Foamy Virus

Author:

Verschoor Ernst J.1,Langenhuijzen Susan1,van den Engel Saskia1,Niphuis Henk1,Warren Kristin S.2,Heeney Jonathan L.1

Affiliation:

1. Department of Virology, Biomedical Primate Research Centre, Rijswijk, The Netherlands

2. Division of Veterinary and Biomedical Sciences, Murdoch University, Western Australia, Australia

Abstract

ABSTRACT The full-length proviral genome of a foamy virus infecting a Bornean orangutan was amplified, and its sequence was analyzed. Although the genome showed a clear resemblance to other published foamy virus genomes from apes and monkeys, phylogenetic analysis revealed that simian foamy virus SFVora was evolutionarily equidistant from foamy viruses from other hominoids and from those from Old World monkeys. This finding suggests an independent evolution within its host over a long period of time.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

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