Novel Simian Homologues of Epstein-Barr Virus

Author:

Ehlers Bernhard1,Ochs Andreas2,Leendertz Fabian13,Goltz Michael1,Boesch Christophe3,Mätz-Rensing Kerstin4

Affiliation:

1. Robert Koch-Institut, D-13353 Berlin

2. Zoologischer Garten Berlin AG, D-10787 Berlin

3. Max-Planck-Institut für Evolutionäre Anthropologie, D-04103 Leipzig

4. Deutsches Primatenzentrum, D-37077 Göttingen, Germany

Abstract

ABSTRACT Thirty different lymphocryptoviruses (LCV), 26 of them novel, were detected in primates by a panherpesvirus PCR assay. Nineteen LCV from chimpanzees, bonobos, gorillas, and other Old World primates were closely related to Epstein-Barr virus (EBV), the type species of the genus Lymphocryptovirus . Seven LCV originating from New World primates were related to callitrichine herpesvirus 3 (CalHV-3), the first recognized New World LCV. Importantly, a second LCV from gorillas and three LCV from orangutans and gibbons were only distantly related to EBV and CalHV-3. They were tentatively assigned to a novel genogroup of Old World primate LCV. The work described in the paper may also help identify an as yet unknown human LCV.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

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