Exploiting the Natural Diversity of RhlA Acyltransferases for the Synthesis of the Rhamnolipid Precursor 3-(3-Hydroxyalkanoyloxy)Alkanoic Acid-Reference-Cited by-同舟云学术

Exploiting the Natural Diversity of RhlA Acyltransferases for the Synthesis of the Rhamnolipid Precursor 3-(3-Hydroxyalkanoyloxy)Alkanoic Acid

Published:2020-03-02 Issue:6 Volume:86 Page:
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Germer Andrea¹,Tiso Till¹^ORCID,Müller Conrad¹,Behrens Beate²,Vosse Christian²,Scholz Karen²,Froning Matti²,Hayen Heiko²,Blank Lars M.¹

Affiliation:

1. RWTH Aachen University, iAMB (Institute of Applied Microbiology, ABBt), Aachen Biology and Biotechnology, Aachen, Germany

2. University of Münster, Institute of Inorganic and Analytical Chemistry, Münster, Germany

Abstract

The RhlA specificity explains the observed differences in 3-(3-hydroxyalkanoyloxy)alkanoic acid (HAA) congeners. Whole-cell catalysts can now be designed for the synthesis of different congener mixtures of HAAs and rhamnolipids, thereby contributing to the envisaged synthesis of designer HAAs.

Funder

Deutsche Forschungsgemeinschaft

European Commission

Bundesministerium für Bildung und Forschung

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.02317-19

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