Human Gut Faecalibacterium prausnitzii Deploys a Highly Efficient Conserved System To Cross-Feed on β-Mannan-Derived Oligosaccharides-Reference-Cited by-同舟云学术

Human Gut Faecalibacterium prausnitzii Deploys a Highly Efficient Conserved System To Cross-Feed on β-Mannan-Derived Oligosaccharides

Published:2021-06-29 Issue:3 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Lindstad Lars J.¹,Lo Galiana²,Leivers Shaun¹^ORCID,Lu Zijia³,Michalak Leszek¹,Pereira Gabriel V.⁴^ORCID,Røhr Åsmund K.¹,Martens Eric C.⁴^ORCID,McKee Lauren S.³^ORCID,Louis Petra²^ORCID,Duncan Sylvia H.²,Westereng Bjørge¹,Pope Phillip B.¹⁵,La Rosa Sabina Leanti¹⁵^ORCID

Affiliation:

1. Faculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Aas, Norway

2. Gut Health Group, Rowett Institute, University of Aberdeen, Aberdeen, Scotland, United Kingdom

3. Division of Glycoscience, Department of Chemistry, KTH Royal Institute of Technology, AlbaNova University Centre, Stockholm, Sweden

4. Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA

5. Faculty of Biosciences, Norwegian University of Life Sciences, Aas, Norway

Abstract

Commensal butyrate-producing bacteria belonging to the Firmicutes phylum are abundant in the human gut and are crucial for maintaining health. Currently, insight is lacking into how they target otherwise indigestible dietary fibers and into the trophic interactions they establish with other glycan degraders in the competitive gut environment.

Funder

The Research Council of Norway

European Research Commission Starting Grant Fellowship

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.03628-20

Reference60 articles.

1. The abundance and variety of carbohydrate-active enzymes in the human gut microbiota

2. The gut microbiota, bacterial metabolites and colorectal cancer