Valproic Acid Inhibits Chronic Toxoplasma Infection and Associated Brain Inflammation in Mice-Reference-Cited by-同舟云学术

Valproic Acid Inhibits Chronic Toxoplasma Infection and Associated Brain Inflammation in Mice

Published:2021-09-17 Issue:10 Volume:65 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Enshaeieh Marjan¹²,Saadatnia Geita¹,Babaie Jalal²^ORCID,Golkar Majid²^ORCID,Choopani Samira³,Sayyah Mohammad³

Affiliation:

1. Department of Biotechnology, Iranian Research Organization for Science and Technology (IROST), Tehran, Iran

2. Molecular Parasitology Laboratory, Department of Parasitology, Pasteur Institute of Iran, Tehran, Iran

3. Department of Physiology and Pharmacology, Pasteur Institute of Iran, Tehran, Iran

Abstract

Individuals infected with Toxoplasma gondii are prone to psychobehavioral disorders, most notably schizophrenia and bipolar disorder. Valproic acid reportedly inhibits the proliferation of T. gondii tachyzoites in vitro .

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.01003-21

Reference54 articles.

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