Clinical Application of a Dot Blot Test for Diagnosis of Enteric Fever Due to Salmonella enterica Serovar Typhi in Patients with Typhoid Fever from Colombia and Peru

Author:

Cardona-Castro Nora1,Gotuzzo Eduardo2,Rodriguez Monica1,Guerra Humberto2

Affiliation:

1. Instituto Columbiano de Medicina Tropical, AA 52162 Medellı́n, Colombia,1 and

2. Hospital Cayetano Heredia—Instituto de Medicina Tropical Alexander von Humbolt, Lima 100, Perú2

Abstract

ABSTRACT Clinical application of a dot blot test to detect immunoglobulin G (IgG) (88% sensitivity and specificity) and IgM (12.1% sensitivity and 97% specificity) against flagellar antigen from Salmonella enterica serovar Typhi was performed in Peruvian and Colombian patients with typhoid fever. This test can be used as a good predictor of serovar Typhi infection in regions lacking laboratory facilities and in field studies.

Publisher

American Society for Microbiology

Subject

Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy

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