Protection against Brucella melitensis or Brucella abortus in mice with immunoglobulin G (IgG), IgA, and IgM monoclonal antibodies specific for a common epitope shared by the Brucella A and M smooth lipopolysaccharides-Reference-Cited by-同舟云学术

Protection against Brucella melitensis or Brucella abortus in mice with immunoglobulin G (IgG), IgA, and IgM monoclonal antibodies specific for a common epitope shared by the Brucella A and M smooth lipopolysaccharides

Published:1992-01 Issue:1 Volume:60 Page:312-315
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Cloeckaert A¹,Jacques I¹,de Wergifosse P¹,Dubray G¹,Limet J N¹

Affiliation:

1. Unit of Experimental Medicine, Catholic University of Louvain, Brussels, Belgium.

Abstract

Mice passively immunized prior to a challenge infection with immunoglobulin G (IgG) and IgM monoclonal antibodies (MAbs) specific for a common epitope of both A- and M-dominant strains had viable Brucella abortus 544 or Brucella melitensis H38 counts in the spleen reduced to the same extent as did mice passively immunized with MAbs specific for either the A or the M epitope. The IgA MAb was not effective.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.60.1.312-315.1992

Reference12 articles.

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4. Cloeckaert A. P. de Wergifosse G. Dubray and J. N. Limet. 1990. Identification of seven surface-exposed Brucella outer NOTES 315

5. Use of monoclonal antibodies to identify the distribution of A and M epitopes on smooth Brucella species;Douglas J. T.;J. Clin. Microbiol.,1988

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