Inhibitory Effect of Antiserum to Surface Antigen P50 of Babesia gibsoni on Growth of Parasites in Severe Combined Immunodeficiency Mice Given Canine Red Blood Cells-Reference-Cited by-同舟云学术

Inhibitory Effect of Antiserum to Surface Antigen P50 of Babesia gibsoni on Growth of Parasites in Severe Combined Immunodeficiency Mice Given Canine Red Blood Cells

Published:2004-03 Issue:3 Volume:72 Page:1795-1798
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Fukumoto Shinya¹,Xuan Xuenan¹,Takabatake Noriyuki¹,Igarashi Ikuo¹,Sugimoto Chihiro¹,Fujisaki Kozo¹,Nagasawa Hideyuki¹,Mikami Takeshi²,Suzuki Hiroshi¹

Affiliation:

1. National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555

2. Laboratory of Veterinary Public Health, College of Bioresource Science, Nihon University, 1866 Kameino, Fujisawa, Kanagawa 252-8510, Japan

Abstract

ABSTRACT The inhibitory effect of an antiserum to surface protein P50 of Babesia gibsoni on the growth of the parasite was determined with severe combined immunodeficiency mice given canine red blood cells. The antiserum to the recombinant P50 protein significantly inhibited the parasite growth, indicating that P50 might be a useful vaccine candidate.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.72.3.1795-1798.2004

Reference18 articles.

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