Serum Antibodies to Pneumococcal Neuraminidase NanA in Relation to Pneumococcal Carriage and Acute Otitis Media-Reference-Cited by-同舟云学术

Serum Antibodies to Pneumococcal Neuraminidase NanA in Relation to Pneumococcal Carriage and Acute Otitis Media

Published:2006-10 Issue:10 Volume:13 Page:1177-1179
ISSN:1556-6811
Container-title:Clinical and Vaccine Immunology
language:en
Short-container-title:Clin Vaccine Immunol

Author:

Simell Birgit¹²,Jaakkola Teija¹²,Lahdenkari Mika¹²,Briles David¹²,Hollingshead Susan¹²,Kilpi Terhi M.¹²,Käyhty Helena¹²

Affiliation:

1. National Public Health Institute, Helsinki, Finland

2. University of Alabama, Birmingham, Alabama

Abstract

ABSTRACT Pneumococcal neuraminidase, NanA, is a pneumococcal vaccine candidate. Prior culture-confirmed pneumococcal contacts were shown to induce serum anti-NanA antibodies during the first 2 years of life. The antibody concentrations at neither 12 nor 18 months were significantly associated with the risk of subsequent pneumococcal carriage or acute otitis media.

Publisher

American Society for Microbiology

Subject

Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy

Link

https://journals.asm.org/doi/pdf/10.1128/CVI.00257-06

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