False-Positive Rate of a “Fourth-Generation” HIV Antigen/Antibody Combination Assay in an Area of Low HIV Prevalence-Reference-Cited by-同舟云学术

False-Positive Rate of a “Fourth-Generation” HIV Antigen/Antibody Combination Assay in an Area of Low HIV Prevalence

Published:2010-10 Issue:10 Volume:17 Page:1642-1644
ISSN:1556-6811
Container-title:Clinical and Vaccine Immunology
language:en
Short-container-title:Clin Vaccine Immunol

Author:

Kim Sinyoung¹²,Lee Jong-Han¹²,Choi Jun Yong¹²,Kim June Myung¹²,Kim Hyon-Suk¹²

Affiliation:

1. Departments of Laboratory Medicine

2. Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea

Abstract

ABSTRACT We retrospectively analyzed the performance of the Architect HIV antigen/antibody (Ag/Ab) combination assay in a tertiary health care center with a situation of low HIV prevalence. The specificity and positive predictive value (PPV) were 99.78% and 31.21%, respectively. However, the specificity and PPV could increase to 99.99% and 89.70% using an arbitrary cutoff value.

Publisher

American Society for Microbiology

Subject

Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy

Link

https://journals.asm.org/doi/pdf/10.1128/CVI.00258-10

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