In Vitro Activities of 10 Antifungal Drugs against 508 Dermatophyte Strains-Reference-Cited by-同舟云学术

In Vitro Activities of 10 Antifungal Drugs against 508 Dermatophyte Strains

Published:2001-09 Issue:9 Volume:45 Page:2524-2528
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Fernández-Torres B.¹,Carrillo A. J.²,Martı́n E.³,Del Palacio A.⁴,Moore M. K.⁵,Valverde A.³,Serrano M.³,Guarro J.¹

Affiliation:

1. Unitat de Microbiologı́a, Facultat de Medicina and Institut d'Estudis Avançats, Universitat Rovira i Virgili, Reus,1

2. Department of Microbiology, Asesorı́a Cientı́fica y de Investigación Aplicada, Barcelona,2

3. Hospital de Valme, Sevilla,3 and

4. Hospital 12 de Octubre, Madrid,4Spain, and

5. St. Thomas's Hospital, London, United Kingdom5

Abstract

ABSTRACT We have tested 508 strains belonging to 24 species of dermatophytes against 10 antifungal drugs following mainly the NCCLS (M38-P) standard for filamentous fungi. However, several important factors, such as the temperature (28 versus 35°C) and time of incubation (4 to 10 days versus 21 to 74 h), have been modified. The antifungals used were itraconazole, ketoconazole, miconazole, clotrimazole, voriconazole, terbinafine, amphotericin B, fluconazole, UR-9825, and G-1. In general, with the exception of fluconazole and G-1, all antifungals were shown to be highly effective.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.45.9.2524-2528.2001

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