Affiliation:
1. Unitat de Microbiologia, Facultat de Medicina, Universitat Rovira i Virgili, Reus, Spain
Abstract
ABSTRACT
We used a modified reference microdilution method (the M-38P method) to evaluate the in vitro activities of the new triazole UR-9825 in comparison with those of amphotericin B against 77 strains of opportunistic filamentous fungi. UR-9825 was clearly more active than amphotericin B against all fungi except
Fusarium solani
and
Scytalidium
spp. Notably, UR-9825 had low MICs for
Aspergillus fumigatus
and
Paecilomyces lilacinus
(MICs at which 90% of isolates are inhibited, 0.125 μg/ml for both species).
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Cited by
45 articles.
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