Molecular typing of Helicobacter pylori isolates from a multicenter U.S. clinical trial by ureC restriction fragment length polymorphism

Author:

Shortridge V D1,Stone G G1,Flamm R K1,Beyer J1,Versalovic J1,Graham D W1,Tanaka S K1

Affiliation:

1. Abbott Laboratories, Abbott Park, Illinois 60064-3500, USA. dee.shortridge@abbott.com

Abstract

The molecular typing of 81 pretreatment Helicobacter pylori isolates and the comparison of 18 pretreatment-posttreatment pairs is described by restriction fragment length polymorphism (RFLP) of the ureC gene. The results of our study show the extreme genomic diversity of H. pylori and indicate that infection by H. pylori in the United States does not appear to be limited to a small number of RFLP types.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference12 articles.

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