Reinvestigating the Coughing Rat Model of Pertussis To Understand Bordetella pertussis Pathogenesis

Author:

Hall Jesse M.12,Kang Jason12ORCID,Kenney Sophia M.12,Wong Ting Y.12,Bitzer Graham J.12,Kelly Claire O.12,Kisamore Caleb A.12,Boehm Dylan T.12,DeJong Megan A.12,Wolf M. Allison12,Sen-Kilic Emel12,Horspool Alexander M.12,Bevere Justin R.12,Barbier Mariette12ORCID,Damron F. Heath12ORCID

Affiliation:

1. Department of Microbiology, Immunology and Cell Biology, School of Medicine, West Virginia University, Morgantown, West Virginia, USA

2. Vaccine Development Center, WVU Health Sciences Center, Morgantown, West Virginia, USA

Abstract

Bordetella pertussis is a highly contagious bacterium that is the causative agent of whooping cough (pertussis). Currently, acellular pertussis vaccines (aP, DTaP, and Tdap) are used to prevent pertussis disease.

Funder

Division of Science and Research, WV Higher Education Policy Commission

HHS | Centers for Disease Control and Prevention

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

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