Maternal immunization with gametocyte antigens as a means of providing protective immunity against Eimeria maxima in chickens

Author:

Wallach M1,Halabi A1,Pillemer G1,Sar-Shalom O1,Mencher D1,Gilad M1,Bendheim U1,Danforth H D1,Augustine P C1

Affiliation:

1. Kuvin Centre for the Study of Infectious and Tropical Diseases, Hebrew University-Hadassah Medical School, Jerusalem, Israel.

Abstract

In the present study, we wished to demonstrate the ability of surface gametocyte antigens to induce protective immunity against Eimeria maxima infections in chickens. In order to accomplish this goal, we employed maternal immunization as a means of providing large amounts of specific antibodies to offspring chicks. Upon challenge with sporulated E. maxima oocysts, chicks from hens immunized with affinity-purified gametocyte antigens showed greatly reduced oocyst production compared with chicks from sham-immunized hens. These results suggest that maternal immunization with gametocyte antigens can be used as a means to provide transmission-blocking immunity against E. maxima infections.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

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5. Immunity to coccidiosis: protective effect of transferred serum in Eimeria maxima infections;Rose M. E.;Parasitology,1971

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